Micky van de Ven Brace Halts The Toffees' Unbeaten Streak at Brand New Home Ground
The Dutch defender became the initial defender to score two goals in a English top-flight match for Spurs since Jan Vertonghen in spring 2013.
At a glance
The Spurs defender heads home twice in opening period
Everton's defender has equalizer ruled after video check
Senegalese midfielder scores third in dying moments
This loss is the Merseyside club's first at Hill Dickinson Stadium
Micky van de Ven scored on two occasions as Spurs prolonged their unbeaten run in away games in the top division and delivered the Toffees their initial loss at Hill Dickinson Stadium.
The Toffees were undefeated in their last five matches at their recently opened stadium at the dockside location, having left their historic home behind after more than a century at the conclusion of last season.
But Spurs captain Van de Ven struck twice from corners in the first half to place their strong form at risk, and they were unable to turn it around before the midfielder - set up by ex-Everton forward the Brazilian - headed home a final goal to put the game to bed.
Jake O'Brien believed he had levelled the scores five minutes after the defender's first goal, glancing a powerful header past the Spurs keeper from an Everton corner.
The Portuguese striker, meanwhile, failed to convert a handful of opportunities, while Vicario made a succession of fine saves to guarantee the London club went five away games without defeat in the Premier League.
But the VAR intervened, instructing Craig Pawson to check the goal on the screen and the official decided that the winger and the attacker were in an illegal position and had interfered with the Tottenham goalkeeper.
The win elevates the manager's side into third place in the division, five points off local foes and leaders Arsenal.
The Merseyside club stay in 14th position and are half a dozen points ahead of the drop zone.
Spurs breakdown: Van de Ven excels in role at both ends of the field
Following a uninspiring weekday display in the European competition against Monaco, where they managed a mere two shots on target, Frank opted for the French striker up front instead of former Toffees player the Brazilian.
The summer signing was unable to influence the game before being substituted for Richarlison after 60 minutes on the field, but it turns out he wasn't needed in the end.
Defender Van de Ven converted into an attacking force to be feared.
Spurs' first goal came from a cleverly executed corner routine, with the midfielder directing the ball toward the face of goal for an free the defender to score.
And Ven de Ven - stepping up as skipper in the Argentine's absence - added his second in first-half stoppage time as he outjumped Jordan Pickford to head home.
Van de Ven was equally impressive in defence, partnering well with his defensive colleague as the duo handled excellently with the numerous deliveries thrown their way by Everton.
Toffees breakdown: Everton lacking striker's instinct
The club's new home had been a fortress, but it seems the novelty may have faded somewhat and fans flocked to the gates after the midfielder's third for Tottenham.
The break in the team's winning streak at home will not be a massive concern for David Moyes, but their attacking woes are.
Beto and the other striker - the Toffees' two established strikers - had netted just a single goal between them before the weekend's match.
And they were failed to add to that miserable record on a damp and dreary night on Merseyside.
Beto's form was summed up when he chose to bicycle-kick a golden opportunity from close range, even with having room and time to readjust for a simpler attempt that would have tested Vicario.
The substitute, as well, failed to make an impact after replacing the starter in the second half.
It wasn't for a shortage of chance. The majority of the home side's attacks came through the winger and the forward, who tirelessly delivered threatening balls into the Tottenham box.
Upcoming fixtures for these two sides?
The Toffees: Moyes' men head to Sunderland in the Premier League on Monday, 3 November at 20:00 GMT.
Spurs: The London club go to Newcastle's ground on Wednesday, 29 October for their fourth-round Carabao Cup tie against Newcastle.